Symbol
Name
ID

Il6
interleukin 6
MGI:96559

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes

Gastrointestinal hemorrhage

Retinal hemorrhage

Purpura

Keratoconjunctivitis sicca

Peripheral arteriovenous fistula

Cerebral arteriovenous malformation

Vasculitis

Abnormal cerebral vascular morphology

Stroke

Congestive heart failure

Lymphadenopathy

Splenomegaly

Abnormal retinal vascular morphology

Visceral angiomatosis

Cutis marmorata

Urticaria

Disease(s) Associated with IL6

arteriovenous malformations of the brain

Graves' disease

lymphoplasmacytic lymphoma

Sjogren's syndrome

Mouse Phenotypes

abnormal capillary morphology

abnormal physiological neovascularization

abnormal heart development

abnormal heart morphology

abnormal interventricular septum morphology

decreased heart weight

enlarged heart

abnormal heart ventricle morphology

decreased heart left ventricle wall thickness

decreased heart left ventricle anterior wall thickness

decreased heart left ventricle posterior wall thickness

dilated heart left ventricle

abnormal cardiovascular system physiology

decreased cardiac muscle contractility

vascular inflammation

Availability

Mouse Genotype

Il6^{tm1.1(KOMP)Vlcg}/Il6^{tm1.1(KOMP)Vlcg}

Il6^tm1Kopf/Il6^tm1Kopf

Tg(Gfap-Il6)G167Lms/Tg(Gfap-Il6)G167Lms

Tg(Gfap-Il6)G16Lms/0
Tg(Gfap-lacZ)1Lms/0

Tg(Gfap-Il6)G167Lms/0

Tg(Gfap-Il6)G369Lms/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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